Sheehan's Syndrome
Sheehan's Syndrome
Sheehan's Syndrome is a rare condition that can occur following severe blood loss or extremely low blood pressure during childbirth. It can damage the pituitary gland, leading to reduced hormone production and a condition known as hypopituitarism.
The pituitary gland plays a vital role in controlling many of the body's hormones. When it is damaged, deficiencies can develop in hormones that regulate the adrenal glands, thyroid gland, menstrual cycle, fertility, breast milk production, and growth hormone levels.
Symptoms
Symptoms can develop immediately after childbirth or may take months or even years to become apparent.
Common symptoms may include:
Difficulty breastfeeding or reduced milk supply
Fatigue and lack of energy
Dizziness or feeling faint
Weight gain or difficulty losing weight
Absent or irregular periods
Reduced libido
Loss of underarm or pubic hair
Difficulty coping with illness or physical stress
Poor concentration and memory problems
Because symptoms can develop gradually, diagnosis is sometimes delayed.
Diagnosis
Diagnosis is based on a detailed medical history, particularly any significant bleeding or complications during childbirth.
Investigations may include:
Hormone blood tests
Dynamic endocrine testing
MRI or CT scans of the pituitary gland
Assessment by an endocrinologist
These tests help determine which hormones may be affected and exclude other pituitary conditions.
Treatment
Treatment focuses on replacing any hormones that the pituitary gland is no longer producing adequately.
Depending on individual needs, treatment may include:
Hydrocortisone or other steroid replacement
Thyroid hormone replacement (Levothyroxine)
Oestrogen and progesterone replacement therapy
Growth hormone replacement therapy
Other hormone treatments where required
Most hormone replacement therapies are long-term and require regular monitoring by an endocrinologist.
Living with Sheehan's Syndrome
With appropriate treatment and ongoing specialist care, most people with Sheehan's Syndrome can lead full and active lives.
If you require steroid replacement therapy, it is important to learn "sick day rules" and carry appropriate emergency steroid identification, such as a steroid card, medical alert jewellery, or a digital medical ID.
Regular follow-up appointments and blood tests are essential to ensure hormone replacement therapy remains effective.
Support and Information
At Pituitary Ireland, we provide information, support, and signposting for people living with Sheehan's Syndrome and other pituitary conditions.
Additional trusted resources are available from:
The Pituitary Foundation – providing comprehensive patient information, educational resources, and support services for people affected by pituitary conditions.
Maternal Pituitary Support – a specialist support organization dedicated to women affected by Sheehan's Syndrome and other pituitary conditions related to pregnancy, childbirth, and the post-partum period.
If you have concerns about symptoms, diagnosis, or treatment, always seek advice from your endocrinologist, GP, or specialist healthcare team.